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崔剑方
研究助理教授
化学系
崔剑方 博士
南方科技大学化学系研究助理教授（副研究员），深圳市海外高层次人才（ “孔雀计划”C 类）。2006年本科毕业于中山大学化学与化学工程学院；2011 年博士毕业于中国科学院上海有机化学研究所。2011 年-2012 年在中国科学院上海有机化学研究所担任助理研究员。 2012-2018 年在香港理工大学应用生物及化学科技系先后担任Research Associate, Postdoctoral Fellow 和Research Fellow 等职位, 在此期间还曾兼任理大科技及顾问有限公司（POLYU TECHNOLOGY & CONSULTANCY COMPANY LIMITED）的科技顾问。2018 年加入南方科技大学化学系任研究助理教授。崔剑方博士长期从事配位化学、金属有机化学和不对称催化的研究，在发展手性四苯并环辛四烯为骨架的新型手性配体/催化剂和手性金(III)络合物方面取得了不错的成绩。至今已经在Angew. Chem.Int. Ed.，Chem. Sci.，Org. Lett.，Chem. Commun.，Adv. Synth. Catal.等著名国际化学期刊共发表论文20多篇，获得国家发明专利（授权）1 篇。
ORCID: https://orcid.org/0000-0003-4186-0595
个人简介
个人简介
研究领域
1） 不对称催化：手性四苯并环辛四烯为骨架的新型手性配体/催化剂的合成，用于不对称催化方法学研究。
2） 金属有机化学：设计与合成手性Au（III）络合物，探讨其结构与反应活性，及其在不对称催化反应中的应用。
3） 小分子荧光探针、功能分子合成。
学术成果 查看更多
已发表论文：(# 共同第一作者；* 通讯作者)
Hao-Ran Ma, Xiao-Shui Peng, Jian-Fang Cui*, Henry N. C. Wong*. Emerging optically active tetraphenylenes: advance and challenge in synthesis and applications in asymmetric catalysis and chiral functional materials. Tetrahedron Lett. 2023, https://doi.org/10.1016/j.tetlet.2023.154429.
Wa-Yi O#, Jian-Fang Cui#*, Qiong Yu, Karen Ka-Yan Kung, Sai-Fung Chung, Yun-Chung Leung*, Man-Kin Wong*. Isoindolium-based Allenes: reactivity studies and applications in fluorescence temperature sensing and cysteine bioconjugation. Angew. Chem. Int. Ed. 2023, e202218038.
Jia Guo, Hao-Ran Ma, Wen-Bin Xiong, Luoyi Fan, You-Yun Zhou*, Henry N. C. Wong*, Jian-Fang Cui*. Iridium-catalyzed enantioselective alkynylation and kinetic resolution of alkyl allylic alcohols. Chem. Sci. 2022, 13, 13914-13921.
Ming-Shang Liu, Hai-Wu Du, Jian-Fang Cui, Wei Shu*. Intermolecular metal-free cyclopropanation and aziridination of alkenes with XH2 (X = N, C) by thianthrenation. Angew. Chem. Int. Ed. 2022, 61, e2022099.
Jia Guo, Wen-Bin Xiong, Hao-Ran Ma, Luoyi Fan, You-Yun Zhou, Henry N. C. Wong, Jian-Fang Cui*. Optical resolution of 1,16-dihydroxytetraphenylene by chiral gold(III) complexation and its applications as chiral ligands in asymmetric catalysis. Chem. Sci. 2022, 13, 4608-4615.
Jian-Fang Cui#, Qiong Yu#, Wa-Yi O#, Li-Wu Huang, Bin Yang, Man-Kin Wong*. Synthesis of 1H-isoindoliums by electrophile-mediated cascade cyclization/iodination of propargylamine-based 1,6-diynes. Org. Biomol. Chem. 2022, 20, 3755.
Hok-Ming Ko, Jie-Ren Deng, Jian-Fang Cui, Karen Ka-Yan Kung*, Yun-Chung Leung*, Man-Kin Wong*. Selective modification of alkyne-linked peptides and proteins by cyclometalated gold(III) (C^N) complex-mediated alkynylation. Bioorg. Med. Chem. 2020, 28, 115375.
Zuo-Cheng Qiu, Yan Zhang, Hui-Hui Xiao, Christina Chui-Wa Poon, Xiao-Li Li, Jian-Fang Cui, Man-Kin Wong, Xin-Sheng Yao, Man-Sau Wong*. 8-Prenylgenistein exerts osteogenic effects via ER α and Wnt-dependent signaling pathway. Exp. Cell Res. 2020, 395, 112186.
Jie-Ren Deng, Sai-Fung Chung, Alan Siu-Lun Leung, Wai-Ming Yip, Bin Yang, Man-Chung Choi, Jian-Fang Cui, Karen Ka-Yan Kung, Zhen Zhang, Kar-Wai Lo, Yun-Chung Leung*, Man-Kin Wong*. Chemoselective and photocleavable cysteine modification of peptides and proteins using isoxazoliniums. Commun. Chem. 2019, 2, DOI: 10.1038/s42004-019-0193-5.
Jia-Jun Jiang#, Jian-Fang Cui#, Bin Yang, Yulu Ning, Nathanael Chun-Him Lai, Man-Kin Wong*. Chiral Cyclometalated oxazoline gold(III) complex-catalyzed asymmetric carboalkoxylation of alkynes. Org. Lett. 2019, 21, 6289-6294.
Jian-Fang Cui#, Bin Yang#, Qiong Yu, Nathanael Chun-Him Lai, Han Chen, Man-Kin Wong*. Silver-mediated organic transformations of propargylamines to enones, α-thioketones, and isochromans. Chemistry Select 2019, 4, 1476-1482.
Jian-Fang Cui, Ri-Shi Tang, Bin Yang, Nathanael Chun-Him Lai, Jie-Ren Deng, Man-Kin Wong*. Metal-Free cyclocarboamination of ortho-formyl phenylacetylenes with secondary amines: access to 1,3-diamino-1H-indenes and 3-amino-1-indanones. Adv. Synth. Catal. 2019, 361, 569-577.
Jian-Fang Cui, Hok-Ming Ko, Ka-Pan Shing, Jie-Ren Deng, Nathanael Chun-Him Lai, Man-Kin Wong*. C,O-Chelated BINOL/gold(III) complexes: synthesis and catalysis with tunable product profiles. Angew. Chem. Int. Ed. 2017, 56, 3074-3079.
Bin Yang, Jian-Fang Cui*, Man-Kin Wong*. Selective C-H bond hydroxylation of cyclohexanes in water by supramolecular control. RSC Adv. 2017, 7, 30886-30893.
Tsz-Wai Hui#, Jian-Fang Cui#, Man-Kin Wong*. Modular synthesis of propargylamine modified cyclodextrins by a gold(III)-catalyzed three-component coupling reaction. RSC Adv. 2017, 7, 14477-14480.
Franco King-Chi Leung, Jian-Fang Cui, Tze-Wai Hui, Karen Ka-Yan Kung, Man-Kin Wong*. Photooxidative amidation of aldehydes with amines catalyzed by rose bengal. J. Org. Chem. 2015, 4, 533-536.
Jian-Fang Cui, Karen Ka-Yan Kung, Hok-Ming Ko, Tsz-Wai Hui, Man-Kin Wong*. Silver-catalyzed transformation of propargylic amine N-oxides to enones and acyloxy ketones via isoxazolinium intermediates. Adv. Synth. Catal. 2014, 356, 2965-2973.
Karen Ka-Yan Kung, Hok-Ming Ko, Jian-Fang Cui, Hiu-Chi Chong, Yun-Chung Leung, Man-Kin Wong*. Cyclometalated gold(III) complexes for chemoselective cysteine modification via ligand controlled C-S bond-forming reductive elimination. Chem. Commun. 2014, 50, 11899-11902.
Franco King-Chi Leung, Jian-Fang Cui, Tsz-Wai Hui, Zhong-Yuan Zhou, Man-Kin Wong*. Hydrogen bond donor–acceptor–donor organocatalysis for conjugate addition of benzylidene barbiturates via complementary DAD–ADA hydrogen bonding. RSC Adv. 2014, 4, 26748-26756.
Hok-Ming Ko, Karen Ka-Yan Kung, Jian-Fang Cui, Man-Kin Wong*. Bis-cyclometallated gold(III) complexes as efficient catalysts for synthesis of propargylamines and alkylated indoles. Chem. Commun. 2013, 49, 8869-8871.
Jian-Fang Cui, Chao Chen, Xiang Gao, Zong-Wei Cai, Jian-Wei Han, Henry Nai Ching Wong*. 2,3,10,11-Tetrahydroxytetraphenylene and its application in molecular recognition. Hev. Chim. Acta. 2012, 95, 2604–2620.
Jian-Fang Cui, Hui Huang, Henry Nai Ching Wong*. A concise synthetic approach towards hydroxytetraphenylenes. Synlett 2011, 1018-1022.
Yan Liu, Zhuofeng Ke, Jianfang Cui, Wen-Hua Chen, Lin Ma, Bo Wang*. Synthesis, inhibitory activities, and QSAR study of xanthone derivatives as α-glucosidase inhibitors. Bioorg. Med. Chem. 2008, 16, 7185-7192.
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