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程英升教授，1966年12月生，安徽省合肥市人；同济大学附属同济医院院长；主任医师，博士后导师。亚太介入放射学分会国际执行委员，世界胃肠介入学会委员，亚太肿瘤介入学会理事；中华医学会放射学分会第十六届对比剂使用和安全工作组组长，中华医学会放射学分会介入学组组长，中华医学会放射学分会第十五届委员，中国医师协会介入医师分会第一届和第二届常务委员，中国老年医学学会放射学分会第一届常委，中国医师协会放射医师分会第四届委员，中国医学影像技术研究会放射学分会第五届委员，中国医学装备协会普通放射装备专委会第一届委员，中华医学会放射分会全国委员兼介入专委会副主任委员，中国医师协会介入分会第一届常委，中国医师协会介入分会第一届综合介入专委会副主任委员，中国抗癌协会肿瘤介入专业委员会常务委员；上海医师协会介入分会会长，上海医学会放射专科分会副主任委员和介入学组组长、上海中西医结合学会介入医学分会会长、上海抗癌协会肿瘤介入专业委员会副主任委员、上海医师协会影像医学与核医学分会副会长。获得上海市优秀学术带头人、上海市卫生系统新优秀学科带头人、上海市医学领军人才、上海市领军人才，享受国务院特殊津贴。作为负责人承担国家级课题8项、市部级课题17项；作为主要完成人获得省部级奖15项，其中国家科技进步二等奖1项（第二完成人）、上海市科技进步一等奖1项（第二完成人）、教育部科技进步一等奖（第三完成人）、中华医学科技二等奖1项（第一完成人）。获得授权“贲门支架”欧盟发明专利1项、澳大利亚发明专利1项、中国发明专利2项和实用新型专利3项，申请国家发明专利3项；发表第一作者或通讯作者论文113篇（其中SCI收录50篇，最高影响因子31.041）；主编专著3部，参编专著10部。《世界华人消化杂志》主编、《介入放射学杂志》主编、英文版《介入放射学杂志》共同主编、英文版《介入放射学年鉴》主编；《中华影像医学》编委、《中华介入放射学（电子版）》编委、《Chinese Medical Journal》编委、《中华医学杂志》英文版和《世界放射学杂志》英文版编委、《中华医学科研管理杂志》和《临床放射学杂志》常务编委等职，《中华放射学杂志》、《Materials Science & Engineering C》、《World Journal of Gastroenterology》、《InternationalJournal of Molecular Sciences》、《Journal Current Medical Imaging》、《Cardiovascular & Hematological Disorders-Drug Targets》、《Materials》、《Biomaterials》等杂志审稿人。荣获第二届国之名医“优秀风范”奖、最具领导力的中国医院院长“杰出业绩奖”、“庆祝中华人民共和国成立70周年纪念章”、“上海杰出专科医师奖”、上海市五一劳动奖章。研究方向：非血管和血管介入放射学、消化系统影像诊断学、分子影像学以及人工智能多学科交叉研究
研究方向Research Directions
非血管和血管介入放射学、消化系统影像诊断学、分子影像学以及人工智能多学科交叉研究
2. 机电结构优化与控制 研究内容：在对机电结构进行分析和优化的基础上，运用控制理论进行结构参数的调整，使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容：以仿生结构为研究对象，运用连续体结构拓扑优化设计理论和方法，对多相仿生结构(机构)材料进行2. 机电结构优化与控制 研究内容：在对机电结构进行分析和优化的基础上，运用控制理论进行结构参数的调整，使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容：以仿生结构为研究对象，运用连续体结构拓扑优化设计理论和方法，对多相仿生结构(机构)材料进行整体布局设计。 整体布局设计。
科研项目
近5年来承担课题：1、国家自然科学基金/基于双药分级控释的可降解镁合金支架治疗犬食管良性狭窄模型的实验研究/编号81371659/2014-1～2017-12/70万元/第一承担人2、国家自然科学基金/具有光敏剂纳米颗粒控释功能的可降解镁合金支架治疗食管恶性梗阻的实验研究/编号81571773/2016-1～2019-12/58万元/第一承担人3、上海市医学领军人才培养/具有光敏剂纳米颗粒控释功能的可降解镁合金支架治疗食管恶性梗阻的实验研究/2016-1～2019-12/45万元/第一承担人4、国家科技部重点研发计划/基于锥束 CT 和灌注技术在脑血管介入治疗中的整合解决方案的研究/编号2017YFC0109204/2017-07～2021-06/95.05万元/第一承担人5、国家自然科学基金/仿生食管水凝胶复合纤维支架治疗食管瘘的实验研究/编号81771943/2018-01～2019-12/25万元/第一承担人6、上海领军人才培养计划/2019-1～2021-12/110万元/第一承担人7、国家自然科学基金/负载BSA-Ce6-MnO2纳米颗粒的可降解光动力支架治疗食管恶性梗阻的实验研究/编号81971714/2020-01～2023-12/55万元/第一承担人8、2019年度申康临床科技创新（新兴前沿）项目/光动力联合食管支架治疗食管恶性梗阻多中心临床研究/SHDC12019122/2019-11～2022-11/50万元/第一承担人
研究成果
近5年第一作者或通讯作者发表的论文：1. Xiaoqing Qian1,2† *, Lingle Zhang3† , Feng Xie4†, Yingsheng Cheng5 * and Daxiang Cui * . Network-BasedPharmacological Study on the Mechanism of Guishao-Liujun Decoction in theTreatment of Gastric Cancer. Frontiers in Pharmacology. Front. Pharmacol. 13:937439. doi: 10.3389/fphar.2022.937439 （IF=5.6, Q1）2. Yining Tao, Chenxu Yan,* Yue Wu, Dan Li, Juan Li, Yuchen Xie,Yingsheng Cheng, Yisheng Xu, Kai Yang,* Wei-Hong Zhu, and Zhiqian Guo*. UnitingDual-Modal MRI/Chemiluminescence Nanotheranostics: Spatially and SensitivelySelf-Reporting Photodynamic Therapy in Oral Cancer. Adv. Funct. Mater. 2023,2303240. DOI: 10.1002/adfm.202303240.（IF=19.00））3. Xing XH, Kuang X, Li X, Cheng YS, Liu FJ.Potential use ofhigh-resolution T2-weighted MRI with histopathologic findings in stagingesophageal cancer. Quant Imaging Med Surg. 2023 Jan 1;13(1):249-258. doi:10.21037/qims-22-376. （IF=2.8/Q2）4. Xiaoqing Qian,Lingle Zhang,Feng Xie,Yingsheng Cheng,DaxiangCui. Network-Based Pharmacological Study on the Mechanism of Guishao-LiujunDecoction in the Treatment of Gastric Cancer. Front Pharmacol . 2022 Jul5;13:937439. doi: 10.3389/fphar.2022.937439. （2021 IF5.988/Q1）5. Lishuai Feng; Chaoran Dou; Yuguo Xia; Benhao Li; MengyaoZhao; Peng Yu; Yuanyi Zheng; Ahm ed Mohamed El-Toni; Nada Farouk Atta; AhmedGalal; Yingsheng Cheng; Xiaojun Cai; Yan Wang; Fan Zhang ; Neutrophil-likeCell-Membrane-Coated Nanozyme Therapy for Ischemic Brain Damage and Long-TermNeurological Functional Recovery, ACS nano, 2021 Feb 23;15(2):2263-2280. doi: 10.1021/acsnano.0c07973.Epub 2021 Jan 11. (2021 15.881/Q1)6. Yiran Zhang#, Yanming Wang#, Li Meng, Qingqing Huang, YueqiZhu, Wenguo Cui*, Yingsheng Cheng*, Ranlu Liu*. Targeted Micelles withChemotherapeutics and Gene Drugs to Inhibit the G1/S and G2/M Mitotic Cycle ofProstate Cancer. Journal of Nanobiotechnology, 2021 Jan 9;19(1):17. doi:10.1186/s12951-020-00756-6.(202110.435/Q2)7. Liu J, Zhou B, Guo Y, Zhang A, Yang K, He Y, Wang J, Cheng Y,Cui D. SR-A-Targeted Nanoplatform for Sequential Photothermal/PhotodynamicAblation of Activated Macrophages to Alleviate Atherosclerosis. ACS Appl MaterInterfaces.2021 Jun 16. doi: 10.1021/acsami.1c06380. Online ahead ofprint.(2021 9.229/Q1)8. Fan S, Zhang Y, Tan H, Xue C, He Y, Wei X, Zha Y, Niu J, LiuY, Cheng Y, Cui D. Manganese/iron-based nanoprobes forphotodynamic/chemotherapy combination therapy of tumor guided by multimodalimaging. Nanoscale. 2021 Mar 18;13(10):5383-5399. doi: 10.1039/d0nr08831e.(2021 7.790/Q1)9. Lishuai Feng, Chaoran Dou, Yuguo Xia, Benhao Li, MengyaoZhao, Ahmed Mohamed El-Toni, Nada Farouk Atta, Yuanyi Zheng, Xiaojun Cai,* YanWang,* Yingsheng Cheng,*and Fan Zhang*. Enhancement of Nanozyme Permeation byEndovascular Interventional Treatment to Prevent Vascular Restenosis viaMacrophage Polarization Modulation. Advanced Functional Materials,2020-12,30(52) DOI: 10.1002/adfm.202006581.(2021 18.808/Q1)10. J Liu，J Gao，A Zhang，Y Guo，S Fan，Y He，K Yang，J Wang，D Cui*，Y Cheng.* Carbonnanocage-based nanozyme as an endogenous H2O2-activated oxygenerator for real-timebimodal imaging and enhanced phototherapy of esophageal cancer. Nanoscale, 2020Nov 5;12(42):21674-21686. doi: 10.1039/d0nr05945e. (2021 7.790/Q1)11. Junyuan Xiao, Yiran Zhang, Tonglei Fang, Tianwen Yuan,Qinghua Tian, Jingjing Liu, Yingsheng Cheng, Yueqi Zhu, Liang Cheng, and WenguoCui. Mineralized manganese dioxide channel as the stent coating for in situprecise tumor navigation. Nano Research. 2020-10 DOI: 10.1007/s12274-020-3114-0（2021 8.897/Q2）12. Junyuan Xiao, Liang Cheng, Tonglei Fang, Yiran Zhang, JiaZhou, Ruoyu Cheng,Wantao Tang, Xiaoyan Zhong, Yong Lu, Lianfu Deng, YingshengCheng,* Yueqi Zhu,*Zhuang Liu,* and Wenguo Cui*. Nanoparticle-EmbeddedElectrospun Fiber–CoveredStent to Assist Intraluminal Photodynamic TreatmentofOesophageal Cancer. Small. 2019Dec;15(49):e1904979. doi:10.1002/smll.201904979. Epub 2019 Oct 28. (2021 13.281/Q1)13. Tonglei Fang# , Junyuan Xiao# , Yiran Zhang, Haiyan Hu ,Yueqi Zhu, Yingsheng Cheng*. Combined with interventional therapy,immunotherapy can create a new outlook for tumor treatment.Quantitative Imagingin Medicine and Surgery. 2021-2, doi: 10.21037/ qims-20-173 .(IF=3.226)14. Junyuan Xiao, Yiran Zhang, Tonglei Fang, Tianwen Yuan,Qinghua Tian, Jingjing Liu, Yingsheng Cheng, Yueqi Zhu, Liang Cheng, and WenguoCui. Mineralized manganese dioxide channel as the stent coating for in situprecise tumor navigation. Nano Research. 2020-10 DOI: 10.1007/s12274-020-3114-0（IF=8.897）15. Yueqi Zhu #, Yingkun He #, Zhongmin Wang, Zhengyu Jin,Chuansheng Zheng, Gang Sun, Haibin Shi, Hailiang Li, Xiao Li, Hua Xiang ,Ligong Lu, Shi Zhou, Tianxiao Li, Xiaoguang Li, Haidong Zhu, Mingsheng Huang,Feng Duan, Haibo Shao, Tianzhi An , Yingsheng Cheng* ; Chinese Society ofInterventional Radiology. Chinese Society of Interventional Radiology ExpertConsensus on the prevention and control of COVID-19 in interventional radiologyprocedures (first edition). Quantitative Imaging in Medicine and Surgery.2020,10(5):1045-1057.(IF=3.226)16. Zhang, Yiran; Wang, Jienan; Xiao, Junyuan; Fang, Tonglei; Hu,Nan; Li, Minghua; Deng, Lianfu; Cheng, Yingsheng; Zhu, Yueqi*; Cui, Wenguo*. Anelectrospun fiber-covered stent with programmable dual drug release forendothelialization acceleration and lumen stenosis prevention. ActaBiomaterialia, 2019-8, 94:295-305, 10.1016/j.actbio.2019.06.008.(2018,IF=6.638).17. Junyuan Xiao, Liang Cheng, Tonglei Fang, Yiran Zhang, JiaZhou, Ruoyu Cheng,Wantao Tang, Xiaoyan Zhong, Yong Lu, Lianfu Deng, YingshengCheng,* Yueqi Zhu,*Zhuang Liu,* and Wenguo Cui*. Nanoparticle-EmbeddedElectrospun Fiber–CoveredStent to Assist Intraluminal Photodynamic TreatmentofOesophageal Cancer. Small. 2019.11. DOI:10.1002/smll.201904979. (SCI IF=10.856)18. Yueqi Zhu, Hongbo Zhang, Yiran Zhang, Huayin Wu, Liming Wei,Gen Zhou, Yuezhou Zhang, Lianfu Deng, Yingsheng Cheng,* Minghua Li,* Hélder A. Santos,* andWenguo Cui. Endovascular Metal Devices for the Treatment of CerebrovascularDiseases. Advanced materials. 2019Feb;31(8):e1805452. DOI: 10.1002/adma.201805452. (SCI IF=25.809)19. Kai Yang, Bi Zhou,Fei Yi, Yan Chen, Yingsheng Cheng*.Colorectal Cancer Diagnostic Algorithm Based on Sub-Patch Weight ColorHistogram in Combination of Improved Least Squares Support Vector Machine forPathological Image. Journal of Medical Systems, 2019 Aug 14;43(9):306. DOI:10.1007/s10916-019-1429-8.(2018,SCI, IF=2.415)20. Kai Yang, Jun Cao, Tian-Wen Yuan, Yue-Qi Zhu, Bi Zhou, Ying-ShengCheng*. Silicone-covered biodegradable magnesium stent for treating benignesophagealstricture in a rabbit model , World Journal of Gastroenterology,2019, 25﴾25﴿:3207-3217, ﴾2018IF=3.411﴿21. Qing‐Hua Tian, Zhong‐Jun Liu, Hei‐Fei Liu, Rui Fang, Rong‐Rong Shen, Tao Wang, Ying‐Sheng Cheng*, and Chun-Gen Wu*. Safety and Efficacy of PercutaneousLumbar Discectomy and Percutaneous Disc Cementoplasty for Painful Lumbar DiscHerniation in Patients over 60 Years. J Vasc Interv Radiol. 2019; 30（June）:894–899. ﴾2018 SCIIF=2.828﴿ 22. Kai Yang, Yue-Qi Zhu, Ni-Wei Chen, Zhi-Gang Wang, Ying-ShengCheng*. Super Flexible Through-the-Scope Self-Expandable Metallic StentInsertion for the Management of Malignant Tortuous Hepatic or Splenic FlexureColonic Obstruction, Chinese Medical Journal, 2018；131(11):1381-1384 (2018,SCI, IF=1.555)
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