个人简介 Personal Profile 兼任中国药理学会, 常务理事；中国药理学会心血管药理专业委员会，常务委员 研究方向为心血管药物药理学，主要涉及心血管炎症和代谢相关损伤的研究。以通讯或共同通讯作者在Acta Pharmacol Sin, Arterioscler Thromb Vasc Biol, Anesthesiology,Hypertension, Redox Biology, Eur Heart J等发表文章30余篇。获国家自然科学基金7项、上海市科委科技创新等资助15项。曾获中国药理学会Servier奖、国家自然科学二等奖(第3)等奖励。 目前在读博士和硕士研究生共11人。 科研项目 在研项目1. 国家自然科学基金 (No.82273922, 52万元)铁死亡介导的STAT4激活在腹主动脉瘤发生发展的作用及机制研究(2023.01-2026.12) 项目负责人2. 上海市科委“科技创新行动计划”(No. 21S11901200, 20万) 肌醇六磷酸盐磷酸激酶3(IP6K3)在非酒精性脂肪性肝病中的作用及机制研究(2021.08-2024.07) 项目负责人3. 国家自然科学基金 (No. 81973312, 55万元) CTRP1抑制NIK/非经典NF-kB2介导的IL-23/IL-17通路延缓腹主动脉瘤发生发展的作用及机制(2020.01-2023.12) 项目负责人4. 上海市协同创新集群(No.2019CXJQ03，99.8万) 精准医学临床实践中的关键分子检测技术研发和转化应用(2019.1-2023.12) 子课题负责人 研究成果 近3年文章1. Zhao Y, Shen QR, Chen YX, Shi Y, Wu WB, Li Q, Li DJ, Shen FM*, Fu H*. Colchicine protectsagainst the development of experimental abdominal aortic aneurysm. Clin Sci(Lond). 2023;137:1533-1545.2. Chi C, Fu H, Li YH, Zhang GY, Zeng FY, Ji QX, Shen QR, Wang XJ,Li ZC, Zhou CC, Sun DY, Fu JT, Wu WB, Zhang PP, Zhang JB, Liu J, Shen FM*, Li DJ*, Wang P*. Exerkinefibronectin type-III domain-containing protein 5/irisin-enriched extracellularvesicles delay vascular ageing by increasing SIRT6 stability. EurHeart J. 2022. doi:10.1093/eurheartj/ehac4313. Fu H, Shen QR, Zhao Y, Ni M, Zhou CC, Chen JK, Chi C, Li DJ, Liang G*, Shen FM*. Activatingalpha7nAChR ameliorates abdominal aortic aneurysm through inhibiting pyroptosismediated by NLRP3 inflammasome. Acta Pharmacol Sin. 2022.https://doi.org/10.1038/s41401 -022-00876-9. 4. Tong J, Li DJ, Meng H, Sun DY, Lan XT, Ni M, Ma JW, Zeng FY,Sun SJ, Fu JT, Li GQ, Ji QX, Zhang GY, Shen QR, Wang YY, Zhu JH, Zhao Y, WangXJ, Liu Y, Ouyang SX, Sheng CQ*, ShenFM*, Wang P*. Targeting a novel inducible GPX4 alternative isoform toalleviate ferroptosis and treat metabolic-associated fatty liver disease. ActaPharm Sin B. 2022. https://doi.org/10.1016 /j.apsb.2022.02.003. 5. Zhou CC, HeYQ, Qiu YS, Ni CX, Shen FM*, Li DJ*.Zinc supplementation ameliorates sorafenib-induced cognitive impairment throughROS/JNK signaling pathway. Biol Trace Elem Res. 2022. doi:10.1007/s12011-022-03142-5. 6. Zhou CC, WangXJ, Li ZC, Lu WJ, Zhang YT, Shen FM*, LiDJ*. Lead Exposure in Developmental Ages Promotes Aβ accumulation bydisturbing Aβ transportation in blood-cerebrospinal fluid barrier/blood-brainbarriers and impairing Aβ clearance in the liver. Biol Trace Elem Res.2021.doi: 10.1007/s12011-021-02969-8. 7. Ni M, Zhao L,Zhang WJ, Ma JW, Zhang GY, Cui DM, Wang K, Fei YB, Gao L*, Shen FM*. Pharmacokinetics of colistin in cerebrospinal fluidafter intraventricular administration alone in intracranial infections. IntJ Antimicrob Agents 2021; 57: 106281.8. Zhou CC, Fu H,Zhang GY, Ma JW, Ni M, Li DJ, Shen FM*, Huang F*. Effects of low-level mercuryexposure on brain-derived neurotrophic factor in preschool children. EcotoxicolEnviron Saf 2021; 208: 111642. 9. Jiang YJ, Sun SJ, Cao WX, Lan XT, Ni M, Fu H, Li DJ, Wang P*, Shen FM*. Excessive ROSproduction and enhanced autophagy contribute to myocardial injury induced bybranched-chain amino acids: Roles for the AMPK-ULK1 signaling pathway andα7nAChR. BBA-Mol Basis Dis 2021; 1867:165980. 学生信息 当前位置：教师主页 > 学生信息 入学日期 所学专业 学号 学位 招生信息 当前位置：教师主页 > 招生信息 招生学院 招生专业 研究方向 招生人数 推免人数 考试方式 招生类别 招生年份
