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个人简介 Personal Profile 2011-09 - 2016-11 南京师范大学 分子生物学 硕博连读、博士2016-12 - 2019-03 上海交通大学 生物医学工程 博士后2019-05 - 至今 加入上海市皮肤病医院王秀丽教授团队担任光医学治疗科 副研究员/同济大学光医学研究所青年PI 研究方向Research Directions 玫瑰痤疮发病机制,皮肤肿瘤发病机制,痤疮发病机制,光动力作用机制 2. 机电结构优化与控制 研究内容:在对机电结构进行分析和优化的基础上,运用控制理论进行结构参数的调整,使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容:以仿生结构为研究对象,运用连续体结构拓扑优化设计理论和方法,对多相仿生结构(机构)材料进行2. 机电结构优化与控制 研究内容:在对机电结构进行分析和优化的基础上,运用控制理论进行结构参数的调整,使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容:以仿生结构为研究对象,运用连续体结构拓扑优化设计理论和方法,对多相仿生结构(机构)材料进行整体布局设计。 整体布局设计。 团队展示   同济大学医学院光医学研究所在学科带头人王秀丽教授的带领下,依托上海市皮肤病医院/同济大学附属皮肤病医院光医学治疗科团队,聚焦“光老化/老年斑/皮肤肿瘤、痤疮、瘢痕、血管瘤”四大专病以及“光医学无创诊断中心”,并已逐步形成光医学特色诊疗平台。    团队成员先后荣获上海市启明星、浦江、扬帆、新百人、新优青等人才培养项目;承担包括科技部国家重点研发计划、国自然等省部级及以上课题70余项;发表SCI论文100余篇,包括Journal of the American Academy of Dermatology,Journal of Investigative Dermatology,British Journal of Dermatology,Journal of the European Academy of Dermatology & Venereology,ACS NANO, Protein Cell,Cell Death & Disease等国际有影响力的杂志;获省部级科技奖9项;相关研究成果在全国3000余家医院推广应用。 项目情况   作为项目负责人先后主持上海市皮肤病医院学术骨干项目,上海市科委面上项目,国自然青年基金,中国博士后基金,作为项目骨干参与科技部国家重点研发计划皮肤肿瘤专项课题和多项国自然面上项目。在Protein Cell,J Am Acad Dermatol,J Eur Acad Dermatol Venereol ,Cell Mol Life Sci,Cancer Letters,Cell Death Disease,Oncoimmunology等杂志发表多篇论文。 科研项目 作为项目负责人先后主持上海市皮肤病医院学术骨干项目,上海市科委面上项目,国自然青年基金,中国博士后基金,作为项目骨干参与科技部国家重点研发计划皮肤肿瘤专项课题和多项国自然面上项目。在Protein Cell,J Am Acad Dermatol,J Eur Acad Dermatol Venereol ,Cell Mol Life Sci,Cancer Letters,Cell Death Disease,Oncoimmunology等杂志发表多篇论文。 研究成果 作为项目负责人先后主持上海市皮肤病医院学术骨干项目,上海市科委面上项目,国自然青年基金,中国博士后基金,作为项目骨干参与科技部国家重点研发计划皮肤肿瘤专项课题和多项国自然面上项目。在Protein Cell,J Am Acad Dermatol,J Eur Acad Dermatol Venereol ,Cell Mol Life Sci,Cancer Letters,Cell Death Disease,Oncoimmunology等杂志发表多篇论文。1. Chen, C.; Wang, P.; Zhang,L.; Liu, X.; Zhang, H.; Cao, Y.; Wang,X*.; Zeng, Q*. Exploring the Pathogenesis and Mechanism-Targeted Treatments of Rosacea: Previous Understanding and Updates. Biomedicines. 2023, 11, 2153. (通讯作者)2. Yang J, Liu X, Cao Y, Wang P, Zhang H, Chen Q, Yang Y, Zeng Q*, Zhang L*, Wang X*. 5-Aminolevulinic acid photodynamic therapy versus minocycline for moderate-to-severe rosacea: A single-center, randomized, evaluator-blind controlled study. J Am Acad Dermatol. 2023 Jun 24. (共同通讯作者)3. Liu P#, Liu X#, Zhang L, Yan G, Zhang H, Xu D, Wu Y, Zhang G, Wang P, Zeng Q*, Wang X*. ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization. Biochem Pharmacol. 2023 Feb;208:115403. (共同通讯作者)4. Zeng Q#, Liu J#, Yan Y, Zhang G, Wang P, Zhang H, Liu X, Zhang L*, Wang X*. Modified 5-aminolevulinic acid photodynamic therapy suppresses cutaneous squamous cell carcinoma through blocking Akt/mTOR-mediated autophagic flux. Front Pharmacol. 2023 Mar 17;14:1114678. (第一作者)5. Cheng Y, Lu X, Li F, Chen Z, Zhang Y, Han Q, Zeng Q, Wu T, Li Z, Lu S, Williams C, Xia W. NDFIP1 limits cellular TAZ accumulation via exosomal sorting to inhibit NSCLC proliferation. Protein Cell. 2023 Mar 16;14(2):123-136.6. Zeng Q#, Yang J#, Ji J, Wang P, Zhang L, Yan G, Wu Y, Chen Q, Liu J, Zhang G*, Wang X*. PD-L1 blockade potentiates the antitumor effects of ALA-PDT and optimizes the tumor microenvironment in cutaneous squamous cell carcinoma. Oncoimmunology. 2022 Apr 3;11(1):2061396. (第一作者)7. Zeng Q#, Yang J#, Yan G, Zhang L, Wang P, Zhang H, Chen Q, Cao Y, Liu X*, Wang X*. Celastrol inhibits LL37-induced rosacea by inhibiting Ca2+/CaMKII-mTOR-NF-κB activation. Biomed Pharmacother. 2022 Sep;153:113292. (第一作者)8. Zeng Q, Zhou C, Zhang Y, Yan G, Wang X*. Modified 5-aminolevulinic acid photodynamic therapy reduces pain and improves therapeutic effects in cutaneous squamous cell carcinoma mouse model. Lasers Surg Med. 2022 Jul;54(5):804-812. (第一作者)9. Wu M, Huang J, Shi J, Shi L, Zeng Q*, Wang H*. Ruyi Jinhuang Powder accelerated diabetic ulcer wound healing by regulating Wnt/β-catenin signaling pathway of fibroblasts In Vivo and In Vitro. J Ethnopharmacol. 2022 Jul 15;293:115321. (共同通讯作者)10. Wu YH#, Wu F#, Yan GR#, Zeng QY, Jia N, Zheng Z, Fang S, Liu YQ*, Zhang GL*, Wang XL*. Features and clinical significance of tertiary lymphoid structure in cutaneous squamous cell carcinoma. J Eur Acad Dermatol Venereol. 2022 Nov;36(11):2043-2050.11. Liu J#, Yan G#, Chen Q, Zeng Q*, Wang X*. Modified 5-aminolevulinic acid photodynamic therapy (M-PDT) inhibits cutaneous squamous cell carcinoma cell proliferation via targeting PP2A/PP5-mediated MAPK signaling pathway. Int J Biochem Cell Biol. 2021 Aug;137:106036. (共同通讯作者)12. Zhang L#, Yang J#, Liu X, Xu D, Shi L, Liu J, Zeng Q*, Wang X*. 5-Aminolaevulinic acid photodynamic therapy amplifies intense inflammatory response in the treatment of acne vulgaris via CXCL8. Exp Dermatol. 2021 Jul;30(7):923-931.  (共同通讯作者)13. Yang J, Shi L, Xu D, Liu J, Zhang L, Liu X, Zeng Q*, Wang X*. 5-Aminolaevulinic acid photodynamic therapy suppresses lipid secretion of primary sebocytes through AMPK/SREBP-1 pathway. Photodiagnosis Photodyn Ther. 2021 Dec;36:102537. (共同通讯作者)14. Zeng Q#, Zhou Z#, Qin S, Yao Y, Qin J, Zhang H, Zhang R, Xu C, Zhang S, Huang S*, Chen L*. Rapamycin inhibits B-cell activating factor (BAFF)-stimulated cell proliferation and survival by suppressing Ca2+-CaMKII-dependent PTEN/Akt-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells. Cell Calcium. 2020 May;87:102171.  (第一作者)15. Cheng Y#, Zeng Q#, Han Q, Xia W*. Effect of pH, temperature and freezing-thawing on quantity changes and cellular uptake of exosomes. Protein Cell. 2019 Apr;10(4):295-299. (共同第一作者)16. Zeng Q#, Hong S#, Wang X#, Cheng Y, Sun J*, Xia W*. Regulation of exosomes secretion by low-intensity pulsed ultrasound in lung cancer cells. Exp Cell Res. 2019 Oct 1;383(1):111448. (第一作者)17. Zeng Q#, Qin S#, Zhang H, Liu B, Qin J, Wang X, Zhang R, Liu C, Dong X, Zhang S, Huang S*, Chen L*. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells. J Cell Physiol. 2018 Jan;233(1):516-529. (第一作者)18. Zeng Q, Zhang H, Qin J, Xu Z, Gui L, Liu B, Liu C, Xu C, Liu W, Zhang S, Huang S*, Chen L*. Rapamycin inhibits BAFF-stimulated cell proliferation and survival by suppressing mTOR-mediated PP2A-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells. Cell Mol Life Sci. 2015 Dec;72(24):4867-84. (第一作者) 学生信息 当前位置:教师主页 > 学生信息 入学日期 所学专业 学号 学位 招生信息 当前位置:教师主页 > 招生信息 招生学院 招生专业 研究方向 招生人数 推免人数 考试方式 招生类别 招生年份

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