个人简介 Personal Profile 浙江大学博士，师从著名半导体专家阙端麟院士和杨德仁院士。现任同济大学医学院博士生导师，同济大学青年岗位能手，上海市分子诊断创新技术研究所CTC中心主任，东方医院血液循环系统精准诊疗研究所执行副所长。重点从事肿瘤液体活检、肿瘤靶向影像和癌症康复治疗研究。作为项目负责人承担十余项国家及省部级科研项目，包括国家自然科学基金面上项目、教育部博士点基金、上海市科委生物医药科技支撑项目、上海市卫健委优青计划等。迄今在Adv. Mater.、ACS Nano、Theranostics等国际知名学术期刊发表SCI论文60 余篇，总引用次数超过3700多次（H因子23），申请国家发明专利 30 多项，已授权 10多项。兼任白求恩精神研究会检验医学分会理事、中国抗癌协会肿瘤标志物委员会CTC专家委员会委员、全国卫生产业企业管理协会转化医学专家委员会委员、全国抗衰老协会肿瘤风险评估与系统康复专委会委员，国家自然科学基金评审专家，教育部学位论文评审专家。 研究方向Research Directions 精准医学与系统生物学,肿瘤液体活检,癌症免疫治疗 2. 机电结构优化与控制 研究内容：在对机电结构进行分析和优化的基础上，运用控制理论进行结构参数的调整，使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容：以仿生结构为研究对象，运用连续体结构拓扑优化设计理论和方法，对多相仿生结构(机构)材料进行2. 机电结构优化与控制 研究内容：在对机电结构进行分析和优化的基础上，运用控制理论进行结构参数的调整，使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容：以仿生结构为研究对象，运用连续体结构拓扑优化设计理论和方法，对多相仿生结构(机构)材料进行整体布局设计。 整体布局设计。 团队展示 科研项目 1. 国家自然科学基金面上项目：批准号：81772285；基于癌细胞表面电荷特性的循 环肿瘤细胞高效捕获与无损释放纳米技术在临床诊断中的应用研究；起止时间： 2018/01~2021/122. 上海市科委生物医药科技支撑项目：批准号：18441900300；基于新型纳米技术 的循环肿瘤细胞检测试剂盒的研发；起止时间：2018/04~2021/063. 上海市卫计委优秀青年医学人才计划：批准号：2017YQ051；新型循环肿瘤细胞 检测纳米技术在临床诊断中的应用研究；起止时间：2017/07~2020/064. 上海市科委西医引导项目：批准号：17411968700；基于癌细胞表面电荷特性新型循环肿瘤细胞检测技术在临床诊断中的应用研究；起止时间：2017/06~2020/065. 国家自然科学基金青年项目：批准号：51302190；新型单壁碳纳米管集成系统在 乳腺癌诊疗中的应用基础研究；起止时间：2014/01~2016/126. 教育部博士点基金：批准号：20130072120029；新型单壁碳纳米管集成系统在乳 腺癌诊疗中的应用基础研究；起止时间：2014/01~2016/127. 上海市卫计委青年科研项目：批准号：20144Y0248；用于循环肿瘤细胞快速灵 敏检测的多功能纳米试剂盒的研发；起止时间：2015/01~2017/128. 硅材料国家重点实验室开放课题：批准号：SKL2014-11；基于微/纳复合结构的 新型柔性纤维状光伏器件的构筑及应用研究；起止时间：2014/08~2016/079. 同济大学青年优秀人才培养计划：批准号：2012KJ022；基于新型非对称纳米结 构的痕量肿瘤细胞检测方法研究；起止时间：2012/12~2014/1210. 中国博士后基金特别资助：批准号：2012T50435；基于新型非对称纳米结构的 痕量肿瘤细胞检测方法研究；起止时间：2012/06~2013/0611：中国博士后基金面上项目：批准号：20100480618；基于单壁碳纳米管的纳米 集成系统的构建及其在乳腺癌诊疗中的应用研究；起止时间：2010/12~2012/12 研究成果 （1） Huixiao Yuan#, Xin Huang#,Qingqing Li#, Cici Luo, Chenyu Lin, Shuxian Zhang, Yaguang Zhang,Zhilin Yan, Ning Du, Zhongmin Liu*, Hua Jiang*, Bingdi Chen*.SiRNA-circFARSA-loadedporous silicon nanomaterials for pancreatic cancer treatment via inhibition ofCircFARSA expression, Biomedicine &Pharmacotherapy, 2022, 147, 112672. (IF=7.419)（2） Jinshan Xu#, Shuxiong Zeng#,Jun Li#, Li Gao, Wenjun Le, Xin Huang, Guandan Wang, Bingdi Chen*, Zhengsheng Zhang*,Chuanliang Xu*. Novel Non-Invasive Diagnosis of Bladder Cancer in Urine Basedon Multifunctional Nanoparticles, Frontiersin Cell and Developmental Biology, 2022, 9, 813420. (IF=6.081)（3） Jing Wang, Wenjun Le, Tinghua Yan, Jinhua Jiang*, Bingdi Chen*. Usage of Nanoparticles toAlter Neutrophils’ Function for Therapy, ACS Biomaterials Science &Engineering, 2022, 8,3676 (IF=5.395)（4） Yao Yao#; Jingyao Chen#;Yuhan Guo; Tian Lv; Zilin Chen; Ning Li; Shaokui Cao; Bingdi Chen*; TaoChen*; Integration of interstitial fluid extraction and glucose detection inone device for wearable non-invasive blood glucose sensors, Biosensors andBioelectronics, 2021, 179: 113078. (IF=12.545)（5） Xin Huang#, Chenyu Lin#, CiciLuo, Yuhan Guo, Jun Li, Yiping Wang, Jiahong Xu, Yuwen Zhang, He Wang*,Zhongmin Liu*, Bingdi Chen*. Fe3O4@Mnanoparticles for MRI-targeted detection in the early lesions ofatherosclerosis, Nanomedicine:Nanotechnology, Biology, and Medicine, 2021, 33, 102348. (IF=6.458)（6） Jing Wang#, Tianxiao Mei#,Yang Liu, Yifan Zhang, Ziliang Zhang, Yihui Hu, Yibin Wang, Minliang Wu,Chuanxue Yang, Xiangdong Zhong, BingdiChen*, Zheng Cui, Wenjun Le*, Zhongmin Liu*. Dual-targeted and MRI-guidedphotothermal therapy via iron-based nanoparticles-incorporated neutrophils, Biomaterials Science, 2021, 9, 3968.(IF=7.590)（7） Chen, Xin#;Wang, Tiegong#; Le, Wenjun; Huang, Xin; Gao, Minghui; Chen, Qian; Xu，Shuogui; Yin, Detao; Fu,Qingge; Shao, Chengwei; Bingdi Chen*; Shi, Donglu; Smart Sorting ofTumor Phenotype with Versatile Fluorescent Ag Nanoclusters by Sensing SpecificReactive Oxygen Species, Theranostics,2020, 10(8): 3430. (IF=11.600)（8） M. L. Wu, T. X. Tian, C. Y. Lin, Y. C. Wang, J. Y.Chen, W. J. Le*, M. Y. Sun, J. G. Xu, H. Y. Dai, Y. F. Zhang, C. Y. Xue*, Z. M.Liu, B. D. Chen*, Melanoma CellMembrane Biomimetic Versatile CuS Nanoprobes for Homologous TargetingPhotoacoustic Imaging and Photothermal Chemotherapy, ACS Applied Materials & Interfaces, 2020, 1214:16031(IF=10.383)（9） M. L. Wu, W. J. Le, T. X. Mei, Y. C.Wang, B. D. Chen*, Z. M. Liu, C. Y. Xue*, Cell membrane camouflagednanoparticles: a new biomimetic platform for cancer photothermal therapy.International Journal of Nanomedicine 2019, 14:4431-4448 (IF=7.033)（10）X. Huang, W. J.Le, Q. Chen, J. Y. Chen, Y. Q. Zhu, D. L. Shi, B. D. Chen*, Z. Cui*,Suppression of the innate cancer-killing activity in human granulocytes bystress reaction as a possible mechanism for affecting cancer development.Stress 2019, DOI: 10.1080/10253890. 2019.1645112. (IF=3.493)（11）W. J. Le, B. D.Chen, Z. Cui, Z. M. Liu*, D. L. Shi*, Detection of cancer cells based onglycolytic-regulated surface electrical charges. Biophysics Reports 2019,5,1:10-18（12）H. H. Zhu, X.F.Li, J.F.Zhu, X.Huang, Q. He, B. D. Chen, W.Cao, Circulating tumor cellsdetected by surface-enhanced Raman scattering technique based on grapheneoxide/gold nanorods. Journal of the Second Military Medical University, 2019,40(6): 643-650.（13）B. B. Zhang, W.Yan, Y. J. Zhu, W.T. Yang, W. J. Le, B. D. Chen*, R. R. Zhu*, L. M. Cheng*,Nanomaterials in Neural‐Stem‐Cell‐Mediated Regenerative Medicine: Imaging andTreatment of Neurological Diseases. Advanced Materials 2018, 30, 1705694(IF=32.086)（14）X. Huang, C. Q.Fan, H. H. Zhu, W. J. Le, S. B. Cui, X. Chen, W. Li, F. Zhang, Y. Huang, D. L.Shi, Z. Cui, C. W. Shao*, B. D. Chen*, Glypican-1-antibody-conjugated Gd–Aunanoclusters for FI/MRI dual-modal targeted detection of pancreatic cancer.International Journal of Nanomedicine 2018, 13:2585-2599 (IF=7.033)（15）Y. L. Tang, L.F. Dong, S. Mao, H. B. Gu, T. Malkoske, B. D. Chen*, Enhanced PhotocatalyticRemoval of Tetrabromobisphenol A by Magnetic CoO@graphene Nanocomposites underVisible-Light Irradiation. ACS Applied Energy Materials 2018, 1, 2698-2708(IF=6.959)（16）W. J. Le, B. D.Chen,, D. Maharaj, Z. Cui*, Natural cancer-killing activity of humangranulocytes. Integrative Cancer Science and Therapeutics 2018, 5, 1-7（17）B. M. Sun, J.Wu, S. B. Cui, H. H. Zhu, W. An, Q. Fu, C. W. Shao, A. H. Yao*, B. D. Chen*,D.L. Shi, In Situ Synthesis of Graphene Oxide/Gold Nanorods Theranostic Hybridsfor Efficient Tumor CT Imaging and Photothermal Therapy. Nano Research 2017,10(1):37-48 (IF=10.269)（18）X. Chen, H. H.Zhu, X. Huang, P. S. Wang, F. L. Zhang, W. Li, G. Chen*, B. D. Chen*, Noveliodinated gold nanoclusters for precise diagnosis of thyroid cancer. Nanoscale,2017, 9(6): 2219-2231(IF=8.307)（19）B. D. Chen, W.J. Le, Y. L. Wang, Z. Q. Li, D. Wang, L. Lin, S. B. Cui, J. J. Hu, Y. H. Hu, P.Y.Yang, R. C. Ewing, D. L. Shi*, Z. Cui* Targeting Negative Surface Charges ofCancer Cells by Multifunctional Nanoprobes. Theranostics 2016, 6, 11:1887-1898(IF=11.600)（20）W. J. Le, S. B.Cui, B. M. Sun, Z. Cui, B. D. Chen*, Non-invasive in vivo targeting humanpancreatic cancer by magnetic resonance imaging. Nanomedicine:Nanotechnology, Biology, and Medicine, 2016, 12(2):529-530(IF=6.458)（21）F. Liu#, W. J.Le#, T. X. Mei, T. G. Wang, L. G. Chen, Y. Lei, S. B. Cui, B. D. Chen*, Z. Cui,C.W. Shao*, In vitro and in vivo targeting imaging of pancreatic cancer using aFe3O4 @SiO2 nanoprobe modified with anti-mesothelin antibody. InternationalJournal of Nanomedicine, 2016, 11:2195-2207 (IF=7.033)（22）W. J. Le#, S. B.Cui#, X. Chen, H. H. Zhu, B. D. Chen*, Z. Cui*, Facile Synthesis ofGd-Functionalized Gold Nanoclusters as Potential MRI/CT Contrast Agents.Nanomaterials, 2016, 6(4):65 (IF=5.719)（23）Y. L. Tang, J.L. Tian, M. Tyler, W. J. Le, B. D. Chen*. Facile ultrasonic synthesis of novelzinc sulfide/carbon nanotubes coaxial nanocables for enhanced photodegradationof Methyl Orange. Journal of Materials Science,2017, 52(3):1581-1589 (IF=4.682)（24）C. X. Peng#, B.D. Chen#, Y. Qin, S. H. Yang, S. L. Liu and J. F. Yang, Facile ultrasonicsynthesis of CoO quantum dot/Graphene nanosheet composites with high lithiumstorage capacity, ACS Nano, 2012, 6(2): 1074-1081 (Co-First Author).(IF=18.027) (ESI)（25）B. D. Chen, H.Zhang, C. X. Zhai, N. Du, C. Sun, J. X. Xue, D. R. Yang, H. Huang, B. Zhang,Q.P. Xie and Y. L. Wu, Carbon nanotube-based magnetic-fluorescent nanohybridsas highly efficient contrast agents for multimodal cellular, J. Mater. Chem.,2010, 20(44): 9895-9902 (IF=6.626)（26）B. D. Chen*, H.Zhang, N. Du, B. Zhang, Y. L. Wu, D. L. Shi and D. R. Yang,Magnetic-fluorescent nanohybrids of carbon nanotubes coated with Eu, Gdco-doped LaF3 as a multimodal imaging probe, J. Colloid Interf. Sci., 2012,367(1): 61-66. (IF=9.965)（27）B. D. Chen, H.Zhang, N. Du, D. S. Li, X. Y. Ma and D. R. Yang, Hybrid nanostructures of Aunanocrystals and ZnO nanorods: layer-by-layer assembly and tunable blue-shiftband gap emission, Mater. Res. Bull. 2009, 44(4): 889-892. (IF=5.600)（28）B. D. Chen, C.X. Peng and Z. Cui, Facile ultrasonic synthesis of CoO/graphene nanohybrids ashigh performance anode materials for lithium ion batteries, T. Nonferr. Metal.SOC. 2012, 22(10): 2517−2522 (IF=3.752)（29）B. D. Chen, Y.Y. Li, B. B. Zhang, B. Zhang, Y. L. Wu and D. L. Shi, Ultraconvenient synthesisof lanthanide based magnetic-fluorescent hydrogels for multimodal cellularimaging, Adv. Mater. Res. 2011, 266, 118-121 (EI)（30）B. D. Chen, T.Zhou, B. Zhang and A. H. Yao, Novel single walled carbon nanotube basedmagnetic-fluorescent nanohybrids as dual-modal MRI/optical imaging probes, Adv.Mater. Res. 2012, 476-478, 1134-1137 (EI)（31）B. D. Chen,Preparation of a magnetic-fluorescent composite system of single-walled carbonnanotubes and rare earth chelates and its application in multimodal imaging,Nanotechnology, 2012, 9: 16-21.（32）X. Zhou, J. Han,Y. F. Wu, B. D. Chen*, Research progress of nanotechnology in tumor targeteddiagnosis and treatment, Journal of Translational Medicine Electronics, 2017,4(2): 10-16.（33）J. Han, X. Zhou, Y. F. Wu, B. D. Chen*,Z. Cui, D. L. Shi, Preparation of a bionavigation nanoprobe for in vitrodetection of prostate cancer cells, Journal of the Second Military MedicalUniversity, 2017, 38 ( 6): 715-719.（34）F. Zhang, D.Chen, Y. Wang, L. Zhang, W. Dong, J. Dai, C. Jin, X. Dong, Y. Sun, H. Zhao, K.Fan, H. Liu, B. Chen, H. Zou, W. Li. Lysosome-dependent necrosis specificallyevoked in cancer cells by gold nanorods. Nanomedicine, 2017, 12(13): 1575–1589(IF=6.096)（35）X. Han, Z. Deng,Z. Yang, Y. Wang, H. Zhu, B. Chen, Z. Cui, RC. Ewing, D. Shi. Biomarkerlesstargeting and photothermal cancer cell killing by surface-electrically-chargedsuperparamagnetic Fe3O4 composite nanoparticles. Nanoscale, 2017, 9:1457-1465.(IF=8.307)（36）Z. H. Xue, T. Wang,B. D. Chen, M. Tyler, S. Yu, Y. L. Tang*. Degradation of Tetracycline withBiFeO3 Prepared by a Simple Hydrothermal Method. Materials, 2015, 8: 6360-6378(IF=3.748)（37）Y. L. Wang, S.Liang, B. D. Chen, F. Guo, S. Yu and Y. Tang, Synergistic removal of Pb(II),Cd(II) and humic acid by Fe3O4@mesoporous silica-graphene oxide composites,PLOS ONE 2013, 8, e65634:1-8 (2013) (IF=3.752)（38）H. Lin*, K.Imakita, M. Fujii*, C. Sun*, B. D. Chen, T. Kanno, H. Sugimoto, New insightsinto the red luminescent bovine serum albumin conjugated gold nanospecies.Journal of Alloys and Compounds 2017, 691: 860-865 (2017) (IF=6.371)（39）M. Z. Lu, W. J. Le, S. B.Cui, B. M. Sun, B. D. Chen, C. W. Shao. Invitro targeting of human pancreatic cancer cells BxPC3 by Mesothelinantibody-modified nanoprobes. Chinese Journalof Pancreatic Diseases, 2014, 14(6): 389-391（40）N. Du, H. Zhang,B. D. Chen, X. Y. Ma, Z. H. Liu, J. B. Wu and D. R. Yang, Porous indium oxidenanotubes: layer-by-layer assembly on carbon-nanotube templates and applicationfor room-temperature NH3 gas sensors, Adv. Mater. 2007, 19, 1641-1645(IF=32.086) (ESI)（41）N. Du, H. Zhang,B. D. Chen, J. B. Wu, X. Y. Ma, Z. H. Liu Y. Q. Zhang, D. R. Yang, X. H. Huangand J. P. Tu, Porous Co3O4 nanotubes derived from Co4(CO)12 clusters on carbonnanotube templates: a highly efficient material for Li-battery applications,Adv. Mater. 2007, 19, 4505-4509 (IF=32.086) (ESI)（42）N. Du, H. Zhang,B. D. Chen, X. Y. Ma and D. R. Yang, One-pot, large-scale synthesis of SnO2nanotubes at room temperature, Chem. Commun. 2008, 3028-3030 (IF=6.065)（43）B. B. Zhang, B.D. Chen, Y. L. Wang, F. F. Guo, Z. Q. Li and D. L. Shi, Preparation of highlyfluorescent magnetic nanoparticles for analytes-enrichment and subsequentbiodetection, J. Colloid Interf. Sci. 2011, 426-432 (IF=7.489)（44）Y. L. Wang, F.Wang, B. D. Chen, H. Xu and D. L. Shi, Facile one-pot synthesis of yolk–shellsuperparamagnetic nanocomposites via ternary phase separations, Chem. Commun.2011, 47, 10350-10352 (IF=9.965)（45）N. Du, H. Zhang,B. D. Chen, X. Ma and D. R. Yang, Ligand-free self-assembly of ceriananocrystals into nanorods by oriented attachment at low temperature, J. Phys.Chem. C 2007, 111, 12677-12680 (IF=4.177)（46）H. Zhang, N. Du,P. Wu, B. D. Chen and D. R. Yang, Functionalization of carbon nanotubes withmagnetic nanoparticles general nonaqueous synthesis and magnetic properties,Nanotechnology 2008, 19, 315604-315609 (IF=3.953)（47）N. Du, H. Zhang,B. D. Chen, J. Wu, D. Li and D. R. Yang, Low temperature chemical reactionsynthesis of single-crystalline Eu(OH)3 nanorods and their thermal conversionto Eu2O3 nanorods, Nanotechnology 2007, 18, 065605-065608 (IF=3.953)（48）C. X. Zhai, H.Zhang, N. Du, B. D. Chen, H. Huang, Y. Wu and D. R. Yang, One-pot synthesis ofbiocompatible CdSe/CdS quantum dots and their applications as fluorescentbiological labels, Nanoscale Res. Lett. 2010, 6, 31-35 (IF=5.418)（49）N. Du, H. Zhang,B. D. Chen, J. Wu and D. R. Yang, Low-temperature chemical reaction routeforZnO based sulfide coxial nanocables: general synthesis and gas sensorapplication, Nanotechnology 2007, 18, 115619-115625 (IF=3.953)（50）T. F. Cui, H.Zhang, N. Du, B. D. Chen, D. Li and Deren Yang, Morphology and phase selectivesynthesis of EuF3 nanostructures by polyelectrolyte assisted chemical reactionand their optical properties, Mater. Chem. Phys.2009, 115, 562-566 (IF=4.778) 学生信息 当前位置：教师主页 > 学生信息 入学日期 所学专业 学号 学位 招生信息 当前位置：教师主页 > 招生信息 招生学院 招生专业 研究方向 招生人数 推免人数 考试方式 招生类别 招生年份
